In a randomised controlled trial, leucocyte-poor platelet-rich plasma (PRP) injections were found to be no more effective than water when injected into Partial Interstitial Rotator Cuff tears. All patients improved over 12 months, but the saline group and the PRP group improved the same amount. The PRP did not stimulate any healing, with the size of the lesions remaining unchanged. It is highly unlikely that leucocyte-poor PRP is useful in this specific condition. More information